Cycobalamin Vitamin B12 Vitamin Antianemia

Cycobalamin Vitamin B12 Vitamin Antianemia

Takaitaccen Bayani:

Cycobalamin yana daya daga cikin hadaddun bitamin B, wanda ke da tasirin anti-pernicious anemia. Sunan da aka bayar ta hanyar crystallization na bitamin B12, wani abu mai mahimmanci ga ci gaban kwayoyin cuta da dabbobi. Bayan C, H, O, N, P da Co, aDribose conjugate na 5,6-dimethe-rbenzimidazole wani bangare ne na tsarinsa. AR Todd et al. gabatar da tsarin tsarin, wanda ake kira cyanocobalamin saboda an haɗa cyano akan cobalt. Matsakaicin sha a cikin maganin ruwa shine 278,361,548 nm. A cikin 1948, E.L. Rickes na Amurka da E.L.Smith na Burtaniya sun fitar da lu'ulu'u da kansu daga hanta. Tun daga wannan lokacin, an kuma samo wannan abu daga wani actinomycete (StrePtomyces griseum).
Cyanocobalamin kuma shine tushen girma na aladu da kaji, kuma abu ɗaya ne da sinadari mai gina jiki na dabba da ake buƙata don ƙyanƙyasar kwai. Vitamin B12, wanda aka ba wa marasa lafiya da cututtuka masu haɗari a 150 micrograms, na iya ƙara yawan jajayen jini da kusan sau 2, kuma 3-6 micrograms na iya haifar da sakamako. A cikin vivo, ana ɗaukar shi a cikin jini ta hanyar haɗin gwiwa tare da furotin trans-cobalamin (protein a-globular), kuma yana wanzuwa ta hanyar coenzyme a cikin kyallen takarda daban-daban. Tare da folic acid, yana da hannu a cikin metabolism na methyl transfer da kuma aiki methyl tsara. Kuma ya zama muhimmin mahimmanci na purine, pyrimidine da sauran biosynthesis.


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